CGR 12: ANTI MDA-5 IN A PAEDIATRIC POPULATION
نویسندگان
چکیده
منابع مشابه
Determination of 5-methyltetrahydrofolate in cerebrospinal fluid of paediatric patients: reference values for a paediatric population.
BACKGROUND Cerebral folate deficiency (CFD) has been described as a neurological syndrome associated with low 5-methyltetrahydrofolate (5-MTHF) values in cerebrospinal fluid (CSF) with normal folate concentrations in plasma. Our aim was to analyse CSF 5-MTHF concentrations in a paediatric control population and in patients with various neurological disorders. METHODS We studied plasma and CSF...
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INTRODUCTION Non-operative management (NOM) is now the primary treatment for blunt splenic injuries in children. Only one study has examined the use of NOM in a Scandinavian population. Thus, the purpose of this study is to report our experience in treating children with blunt splenic injuries with NOM at a Danish university hospital. METHODS We conducted a retrospective observational study o...
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Noroviruses are important human pathogens responsible for most cases of viral epidemic gastroenteritis worldwide. Murine norovirus-1 (MNV-1) is one of several murine noroviruses isolated from research mouse facilities and has been used as a model of human norovirus infection. MNV-1 infection has been shown to require components of innate and adaptive immunity for clearance; however, the initial...
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OBJECTIVE Autoantibodies against melanoma differentiation-associated gene 5 (MDA-5) are one of the serological markers for DM. Anti-MDA-5 antibodies are especially associated with rapidly progressive interstitial lung disease (ILD) in amyopathic DM (ADM). It is known that the antibody status of anti-ENAs does not generally change significantly with disease course. For anti-MDA-5 antibodies, how...
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Received: Nov 23, 2015 Accepted: Dec 22, 2015 Ann Paediatr Rheum 2016;5:24-27 DOI: 10.5455/apr. 122220151559 Introduction Melanoma differentiation-associated gene 5 (MDA-5) plays a role in regulating the innate immune system response against viral infections and in activating the expression of type I interferons [1]. The association of MDA-5 antibodies with connective tissue disease (CTD) has b...
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ژورنال
عنوان ژورنال: Internal Medicine Journal
سال: 2017
ISSN: 1444-0903
DOI: 10.1111/imj.12_13579